Search results for "Continuous variable"
showing 10 items of 16 documents
Association of derived neutrophil-to-lymphocyte ratio (dNLR) with pathological complete response (pCR) after neoadjuvant chemotherapy (CT)
2019
Abstract Background dNLR is a novel biomarker associated with clinical outcome in solid tumors including early stage breast cancer (BC). Here we report the association of dNLR with pCR in triple-negative (TN) and luminal BC patients (pts) treated with neoadjuvant CT. Methods This was a retrospective analysis of two randomized studies (GEICAM/2006-03 - NCT00432172 and ETNA - NCT01822314) involving 821 pts with early stage (>2cm) or locally advanced TN or luminal BC receiving anthracycline/taxane-based CT +/- carboplatin (GEICAM/2006-03) or nab-paclitaxel/paclitaxel followed by anthracycline regimen (ETNA). dNLR was calculated as the ratio of neutrophils and the difference between total leuko…
Monogamy Inequality for Distributed Gaussian Entanglement
2007
We show that for all n-mode Gaussian states of continuous variable systems, the entanglement shared among n parties exhibits the fundamental monogamy property. The monogamy inequality is proven by introducing the Gaussian tangle, an entanglement monotone under Gaussian local operations and classical communication, which is defined in terms of the squared negativity in complete analogy with the case of n-qubit systems. Our results elucidate the structure of quantum correlations in many-body harmonic lattice systems.
Abstract PO-35: Prognostic significance of MYC, BCL2, and BCL6 colocalization at single-cell resolution in DLBCL
2020
Abstract MYC, BCL2, and BCL6 are commonly used markers for immunohistochemistry of Diffuse large B-cell lymphomas (DLBCL). Coexpression of MYC and BCL2 in particular constitutes a subgroup of “double expressor lymphomas” (DEL) with a distinct poor clinical outcome. However, it is not known if MYC and BCL2/BCL6 coexpression occurs in the same cell or in different cells within the tumor, as traditional immunohistochemistry (IHC) is limited by the number of markers that can be simultaneously assessed within formalin-fixed, paraffin-embedded (FFPE) samples. We set out to discover the clinical significance of MYC, BCL2, and BCL6 colocalization at single-cell resolution using multiplexed quantita…
Count data in psychological applied research.
2006
As some authors have noticed in fields other than psychology, level of measurement and distributional characteristics of count data are commonly not taken into account, so that they are analysed as normally distributed continuous variables, and therefore some general linear model is applied. In this work, we review a random sample of 457 articles published in the last four years in journals with the highest impact factor in the Journal Citation Reports (JCR Social Sciences Edition) of the Institute for Scientific Information. The goals are to know how often count variables appear in psychological applied research and which data analyses are used when dealing with count response variables. …
Numerosity Discrimination in Children With Down Syndrome
2009
To understand the difficulties in mathematics exhibited by children with Down syndrome (DS), this study evaluated the core knowledge of numerosities with a discrimination task adapted from Xu and Spelke (2000). Although continuous variables varying with numerosity were controlled, children with DS discriminated the numerosity 8 from 16, but not from 12. Moreover, their performance did not differ from typically developing children matched either on chronological or mental age. Thus, the approximate numerosity system that recruits parietal lobes (Dehaene, Spelke, Pinel, Stanescu, & Tsivkin, 1999) is efficient in children with DS. These findings point at language-based systems as the source of…
The association between sedentary behavior and sarcopenia among adults aged ≥65 years in low-and middle-income countries
2020
The present study aimed to assess the association between sedentary behavior and sarcopenia among adults aged &ge
TCSC allocation based on line flow based equations via mixed-integer programming
2007
Summary form only given. Research effort has been given to locate the optimal locations of thyristor-controlled series capacitor (TCSC) and their initial compensation levels using mixed-integer programming (MIP). As a useful technique for combinatorial optimisation over integer and continuous variables, the MIP approach can provide robust performance as well as high computational efficiency while solving complex optimal problems. Previous work using MIP employed DC load flow model ignoring reactive power balance, power loss and transformer tap ratios. In this paper, a new planning method is developed based on recently reported line flow equations and basic linearisation of binary-continuous…
The Mediating Role of Orthorexia in the Relationship between Physical Activity and Fear of COVID-19 among University Students in Poland
2021
Previous research showed that the COVID-19 pandemic has a significant impact on the wellbeing and lifestyle of populations worldwide, including eating and physical activity (PA) patterns. The present study aims to examine the mediating effect of orthorexia on the relationship between PA and fear of COVID-19. A sample of 473 university students from Poland of a mean age of 22 years (M = 22.04, SD = 2.90, 47% of women) participated in the cross-sectional online survey study. Continuous variables were measured using the Fear of COVID-19 Scale (FCV-19S) and the Test of Orthorexia Nervosa (TON-17), while categorical variables divided participants into the physically active and inactive group reg…
Abstract 4010: Prognostic role of miRNAs in resectable non-small cell lung cancer
2015
Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA BACKGROUND MicroRNAs (miRNA) are a class of small RNAs that regulate gene expression, and are implicated in several diseases including cancer. The aim of this study was to analyze the prognostic implications of deregulated miRNAs identified by NGS in a previous study performed on resectable-NSCLC tumor samples. MATERIAL AND METHODS Fresh-frozen tumor and normal adjacent lung tissue samples (N = 195) were obtained by surgical resection from NSCLC patients and storage in RNAlater® at -80°C until analysis. RNA was isolated biological specimens by Trizol based-methods. 22 deregulated miRNA were analyzed in paired t…
Demonstration of a fully tuneable entangling gate for continuous-variable one-way quantum computation
2015
We introduce a fully tuneable entangling gate for continuous-variable one-way quantum computation. We present a proof-of-principle demonstration by propagating two independent optical inputs through a three-mode linear cluster state and applying the gate in various regimes. The genuine quantum nature of the gate is confirmed by verifying the entanglement strength in the output state. Our protocol can be readily incorporated into efficient multi-mode interaction operations in the context of large-scale one-way quantum computation, as our tuning process is the generalisation of cluster state shaping.